Reflection paper on the use of macrolides, lincosamides and streptogramins in food-producing animals

Sales of macrolides, lincosamides, streptogramins, and amoxicillin/clavulanate in the in- and outpatient setting in 10 European countries, 2007–2010

Monitoring the use of antibiotics is relevant due to the public health impact of microbial resistance, adverse effects, and costs. We present data on the consumption of macrolides, lincosamides, streptogramins and amoxicillin/clavulanate (AMC) between 2007 and 2010 in the in-and outpatient healthcare setting in 10 European countries provided by IMS Health. Antibiotics were classified according ...

Inducible macrolides-lincosamides-streptogramin B resistance in Bacteroides species.

The first evidence is presented for the presence of inducible macrolides-lincosamides-streptogramin B resistance in Bacteroides species. Different macrolides induced clindamycin resistance in Bacteroides vulgatus RYC18F6, an erythromycin-resistant and clindamycin-susceptible strain. A study of 144 Bacteroides isolates indicated that erythromycin resistance was linked to diminished clindamycin s...

Distribution of genes encoding resistance to macrolides, lincosamides, and streptogramins among staphylococci.

The relative frequency of 10 determinants of resistance to macrolides, lincosamides, and streptogramins was investigated by PCR in a series of 294 macrolide-, lincosamide-, and/or streptogramin-resistant clinical isolates of Staphylococcus aureus and coagulase-negative staphylococci isolated in 1995 from 32 French hospitals. Resistance was mainly due to the presence of ermA or ermC genes, which...

Quinupristin/dalfopristin: the first available macrolide-lincosamide-streptogramin antibiotic.

Genome Sequencing of Extended-Spectrum β-Lactamase (ESBL)-Producing Klebsiella pneumoniae Isolated from Pigs and Abattoir Workers in Cameroon

Background and objectives: Extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae is a serious public health issue globally. In this study, the antibiotic resistance genes, virulence factors, mobile genetic elements, and genetic lineages of circulating ESBL-producing K. pneumoniae strains isolated from pigs and humans in Cameroonian abattoirs were investigated using whole genome s...